Simple disk-based method for detection of Klebsiella pneumoniae carbapenemase-type beta-lactamase by use of a boronic acid compound.

نویسندگان

  • Yohei Doi
  • Brian A Potoski
  • Jennifer M Adams-Haduch
  • Hanna E Sidjabat
  • Anthony W Pasculle
  • David L Paterson
چکیده

A disk potentiation method using carbapenems as substrates and 3-aminophenyl boronic acid as an inhibitor was evaluated for the detection of Klebsiella pneumoniae carbapenemase (KPC)-type beta-lactamases. When combined with nonsusceptibility to ertapenem, the method was easy to perform and reliably differentiated isolates producing KPC-type beta-lactamases from those producing other types of beta-lactamases.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 46 12  شماره 

صفحات  -

تاریخ انتشار 2008